Does Prozac Work?
Maybe not.

When all the data was pulled together, it appeared that patients had improved - but those on placebo improved just as much as those on the drugs.
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"Given these results, there seems little reason to prescribe antidepressant medication to any but the most severely depressed patients, unless alternative treatments have failed," says Kirsch. "This study raises serious issues that need to be addressed surrounding drug licensing and how drug trial data is reported."